GLBRC Conversion research aims to increase the quantity, diversity, and efficiency of energy products derived from plant biomass. Researchers focus on improving biological and chemical methods to convert plant material into advanced biofuels or valuable chemicals that can replace petroleum. Basic research discoveries that enhance the efficiency and sustainability of biomass conversion can break down barriers to developing economically viable biofuels technologies.
Scientific Director, Conversion Lead
Landick is an expert on structure, function and regulation of RNA polymerase, the central engine of gene expression. His work spans disciplines from single-molecule biochemistry to genome-scale mechanisms of gene regulation, and includes devising the first single-molecule observation of nucleic...
Within the Conversion group, researchers apply a combination of synthetic biology, directed evolution, systems biology, and computational modeling approaches to accelerate the rate and yield of microbial conversion of biomass to fuels. Microbial efforts focus on well-established models and biofuel-producing organisms to identify key genes and pathways that may illuminate opportunities for strain improvement. Chemical routes focus on direct catalytic conversion of biomass-derived sugars and lignin into liquid transportation fuels and/or high-value chemicals.
Specific Conversion projects fall in three categories:
- Engineering microbe strains to enhance stress tolerance and improve conversion efficiency of sugars to biofuels
- Developing flexible routes to biofuel production that can be adapted to diverse biomass feedstocks
- Producing light-driven and lignin-derived advanced biofuels, and using catalytic conversion to convert biomass to biofuels and value-added chemicals
In silico whole genome sequencer and analyzer (iWGS): a computational pipeline to guide the design and analysis of de novo genome sequencing studies
An engineered solvent system for sugar production from lignocellulosic biomass using biomass derived γ-valerolactone